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The efficacy of setmelanotide may not be sufficient for POMC-MC4R deficient patients because body weight reduction ratio of semaglutide and tirzepatide were 12.4 and 17.8%, respectively in clinical study as compared with that of setmelanotide, 5.2% [[18, 19, 23]]
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size:0.25mg
[DOI] [PubMed] [Google Scholar] 97.Jacobsen L.V., Flint A., Olsen A.K., Ingwersen S.H
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