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The largest study of people eating strictly plant-based found they are about 35 pounds lighter on average, and the most effective weight-loss diet without portion restriction that was ever published in the peer-reviewed medical literature was a whole food, plant-based dietary intervention
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In combination with metformin and rosiglitazone, sitagliptin provided significant improvements in A1C, FPG, and 2-hour PPG compared to placebo with metformin and rosiglitazone (Table 12) at Week 18
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