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But here’s the nuance most people miss: This is not CPAP independence Patients remained on PAP during trials Improvements are largely weight-driven So the correct framing is: ✅ OSA improvement = proven ❌ CPAP replacement = not proven Why this matters commercially OSA is: Diagnosable Specialist-managed Reimbursable That makes it far more valuable than “pure obesity”
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Patients with pre-existing tachyarrhythmias , particularly atrial fibrillation or atrial flutter, should be evaluated carefully before initiating GLP-1 therapy
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